Kazan made her acting debut in Swordswallowers and Thin Men (2003) and later appeared in films such as The Savages (2007), Revolutionary Road (2008), and It’s Complicated (2009). She starred in Happy. Thank You. More. Please. (2010), Meek’s Cutoff (2010), Ruby Sparks (2012), and What If (2013). In 2014, she appeared in the HBO miniseries Olive Kitteridge, for which she received an Emmy nomination. She portrayed Emily Gardner in the film The Big Sick (2017), and in 2018 she appeared in the Coen brothers film The Ballad of Buster Scruggs in the episode “The Gal Who Got Rattled”.
Kazan has acted in several Broadway productions. She also wrote Ruby Sparks and co-wrote Wildlife (2018) with her partner, Paul Dano, who directed the film. In 2020, she appeared in the HBO miniseries The Plot Against America.
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